Mayo Clinic Minute: Tick Bite Linked to Alpha-Gal Meat Allergy

Mayo Clinic Minute: Tick Bite Linked to Alpha-Gal Meat Allergy

You may have heard about Centers for Disease Control and Prevention (CDC), over 110,000 suspected cases of alpha-gal syndrome were identified between 2010 and 2022. However, the actual number may be much higher due to underdiagnosis and lack of awareness among healthcare providers.

What is Alpha-Gal Syndrome and How Do You Get It?

Watch: The Mayo Clinic Minute

Journalists: Broadcast-quality video (0:59) is available for download at the end of this post. Please credit: “Mayo Clinic News Network.” Read the script.

“Alpha-gal is a short abbreviation for galactose-alpha-1, 3-galactose. It’s a sugar molecule found in nonprimate mammalian meats,” explains Dr. Pritt.

This includes meats like beef, pork, lamb, and venison.

“People who develop alpha-gal syndrome after a tick bite become allergic to mammalian meat, except for primate meat,” says Dr. Pritt.

This means poultry, fish, and seafood are safe to consume. The CDC provides a list of food products that may contain alpha-gal.

In the U.S., the primary culprit is the Mayo Clinic medical illustration showing how the lone star tick that has picked up a protein/antigen from a deer and transmitted it to a human. After the tick bite to the human, a standard IgE allergy sensitization reaction occurs<img fetchpriority=